Taxol or Taxotere, which is better?
Taxotere(r) (docetaxel) is superior than Taxol(r) (paclitaxel) in the treatment of metastatic breast cancer in patients who have previously undergone therapy with the chemotherapeutic drug Taxol(r) (paclitaxel), according to a recent report published in the Annals of Oncology.
Why does hormone therapy for prostate cancer cease working for certain patients?
Castration-resistant prostate cancers, those that no longer respond to hormone treatment, are the most common form of the disease. When androgen levels are exceedingly low or undetectable, they continue to develop.
What is the significance of a PSA level of 400?
In high concentrations, PSA is produced into seminal fluid, and it is also present in the blood at relatively low concentrations. In general, PSA values under 4 ng/ml are regarded normal, whereas those above 4 ng/ml are deemed abnormal. Prostate cancer risk is elevated in men with PSA values between 4 and 10 ng/ml.
To what extent might docetaxel harm your eyes?
If you notice any changes in your vision, such as blurry vision, trouble reading, or eye discomfort, notify your doctor immediately. An eye condition known as cystoid macular edoema may cause these symptoms.
When will the Taxotere case be settled?
Taxotere litigation is still continuing in federal court in Louisiana as of March 2022, with 11,979 cases for hair loss and 14 lawsuits for visual impairments. There have been no Taxotere lawsuit payments to date.
In terms of PSA levels, what is the highest that has ever been recorded?
The highest PSA concentration found in this research was 23,162 ng/mL.
Docetaxel has an effect at what point in the cell cycle?
Inhibition of microtubule disintegration, which results in cell cycle arrest during the G2/M phase and cell death, is one of the main mechanisms by which docetaxel exerts its strong and broad-spectrum anticancer effects.
Are cancers reduced by docetaxel?
Various chemotherapy medications, such docetaxel, cisplatin, and carboplatin, limit tumour cell development in different ways. They either kill tumour cells directly or prevent them from multiplying. Cancer cells may be killed by radiation treatment, which employs x-rays with high intensity to decrease tumours.
How powerful is docetaxel?
A lengthy number of adverse effects may be attributed to the primary component, docetaxel, being such a potent chemotherapy treatment. Symptoms such as nausea, vomiting, and temporary hair loss are characteristic with medications in this class (hair loss).
How long after docetaxel should I wait before starting chemotherapy?
Is it possible that I will feel better? During the course of your therapy, you may experience significant fatigue. Even after the therapy is over, some individuals may continue to feel fatigued. It’s possible that your medical staff can assist you in reducing weariness in certain cases. Find out more about exhaustion by reading this article.
Docetaxel’s life-extension effect lasts how long?
Among patients with metastatic illness, docetaxel increased the expected survival time by an average of 0.89 years, and by 0.78 years for those without metastatic disease. Additionally, docetaxel prolonged the discounted QALYs of patients with metastatic cancer by 0.51 years and those without metastatic illness by 0.39 years.
What is the cause of mortality in prostate cancer that has spread?
There were many deaths attributed to heart failure and other external reasons, but a higher percentage of deaths were attributed to disorders of the urinary system or the lungs or anaemia. These disorders have been linked to both PC and its treatment, according to various theories.
Is it possible for metastatic prostate cancer to relapse?
Metastatic prostate cancer frequently responds to hormone therapy and goes into remission when initially treated with it. Cancer cells, on the other hand, might become resistant to therapy. In the absence of male hormones, prostate cancer cells may “learn” to grow.
Does docetaxel have a long-term effect on prostate cancer?
After using docetaxel in combination with standard cancer treatment (hormonal therapy, with or without radiotherapy), the median overall survival rate (OS) was 81% (0.778; 95% CI, 0.66-0.93).